About – Physician Assistant Karl Simon

Background and Education

Karl Simon was born in Houston, Texas, and was an active participant in school and community athletics programs from an early age. After graduating from Clements High School in Sugar Land, where he played varsity baseball, Anthony was accepted to San Jacinto College in Houston, Texas, on a full academic scholarship. He was named an Academic All-American in 2003 and participated in the College World Series in Grand Junction, Colorado the same year. As a high-level collegiate athlete, Karl became a role model for his teammates. His work ethic and enthusiasm helped form strong bonds among team members while helping propel the entire team to success both on and off the field.

Later in 2003, Karl (Anthony) Simon transferred to Houston Baptist University, where he completed his undergraduate coursework. He graduated in 2006 with a Bachelor of Science degree in Biology and Biochemistry. He was also recognized as Magna Cum Laude in his graduating class. Soon after graduation, Mr. Simon enrolled in the Physician Assistant program at the University of Texas Medical Branch-Galveston. Again, his academic career was recognized for excellence, and he graduated in 2009 in the top 5% of his class. While in the program, he developed a Master’s Thesis project entitled “Lead Poisoning in Galveston Children.” His project won the highest honor in the program, attaining Top Project within his graduating class. Lead poisoning among young people in the Galveston area has been a public health crisis for years. Karl’s Thesis served to shine new light on the crisis by encouraging government agencies to develop solutions and to protect the region’s children.

Professional Career

In Houston, Texas, Karl Anthony Simon has performed his duties as a licensed Physician Assistant since graduating from the University of Texas Medical Branch in 2009. His first role was at an orthopedic clinic in Richmond, Texas. Here, he was tasked with assessing new and established orthopedic patients in clinic and in the hospital.  In addition to his administrative and clinical duties, Anthony Simon was also a hospital first responder for orthopedic trauma patients.

In 2013, Simon was appointed a Clinic Director position at a men’s health clinic in Sugar Land. He supervised employees and provided managerial support in training, recruitment and business operations in addition to his work with new and existing patients.

The following year, Karl was named the lead clinician for a large family-oriented primary care, orthopedic and pain management practice in Pasadena, Texas. As in his previous roles, Anthony’s work stood out for his expertise in diagnosing and treating a wide range of medical conditions.

In 2015, Karl got the opportunity to serve a rural critical access hospital in Dalhart, Texas as part of the Dallam Hartley Counties Hospital District. As an emergency clinician, he was responsible for assessing and treating emergency department (ED) patients, including laceration repairs and diagnostic imaging evaluations. He also arranged for inter-hospital transfers for high-acuity patients. This experience would prove valuable, as he was also tasked with performing staff provider duties at multiple ED departments throughout the Houston area coinciding with his work for the rural hospital district. He continued emergency medical services until 2019 when he returned to the men’s health clinic as a part-time care provider. 

Recently, Mr. Simon returned to Houston after being deployed on an assignment with a rapid response team in which he treated patients during the Covid-19 pandemic. His experience in working with patient in critical environments proved invaluable to the rapid response team. With his help, the team was able to prioritize patient needs, speeding treatment to those who needed it most. Karl Anthony Simon is a credit to the profession of Physician Assistant. He continues to apply his talents and care to helping others.

Karl Anthony Simon PA-C, Houston, TX


Karl Anthony Simon holds multiple professional certifications, including:

  • Basic Life Support
  • Pediatric Advanced Life Support (PALS)
  • Advanced Cardiovascular Life Support (ACLS)
  • Advanced Trauma Life Support (ATLS)

Anthony Simon maintains his professional certifications and attends continuing education courses to maintain proficiency in all aspects of healthcare delivery.

The Texas Medical Board